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KMID : 0614720170600060484
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Journal of Korean Medical Association
2017 Volume.60 No. 6 p.484 ~ p.490
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Diagnosis and treatment of Crohn's disease
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Kim Hyun-Soo
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Abstract
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Crohn's disease is a chronic and relapsing disease that is not easily controlled with medications. It is characterized by progressive transmural inflammation, and ultimately leads to stricture and penetrating complications requiring surgery. Over the past decades, the prevalence of Crohn's disease has gradually increased in Korea. Conventional treatments with aminosalicylates, steroids, and immunosuppressants are inadequate to control its symptoms and complications. Biologic therapy shows promise for controlling disease activity and promoting mucosal healing. Despite the development of several medical therapies, the treatment of Crohn's disease remains challenging. Individually tailored treatment according to an endoscopic or symptomatic assessment is required.
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KEYWORD
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Crohn disease, Diagnosis, Therapeutics
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